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The Value of a Dimensional Nosology of Psychiatric Illness: Current Progress and New Research

机译:精神疾病尺寸危害的价值:目前的进展和新研究

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Considerable quantitative evidence has now been amassed suggesting that mental disorders are more accurately understood as continuously distributed dimensions of psychopathology rather than categorical constructs. The result has been an increasing shift towards a dimensional organization of psychopathology in contemporary psychiatry. Data-driven (i.e., factor model-based) modeling of numerous measures of mental disorders and psychopathology has provided robust empirical support for evidence of a transdiagnostic general factor model of psychopathology. The general psychopathology, or “p” factor, reflects both the common variation among all symptoms of psychopathology, as well as low to high psychopathology severity, thus cutting across diverse mental disorder categories and/or symptoms (i.e., those included as input for empirical modeling). This shared variation is consistent with the high rates of comorbidity commonly observed across most classic mental disorder categories. Current methodological work is now addressing important questions concerning the empirical definition of the “p” factor and plausible mechanisms that give rise to the observed interrelationships amongst mental illness (or symptom) indicators (see Watts et al., 2020). As we begin to integrate dimensional symptom measures in clinical practice, it is important to examine the significance of dimensionally-measured constructs, as well as their trajectories across development and across treatment. Such evidence will support an evidence-based approach to identifying children and youth at risk and will inform the timing and nature of prevention and intervention efforts.
机译:现在已经过分了大量的定量证据,表明精神障碍更准确地理解为精神病理学的连续分布尺寸而不是分类构建。结果一直朝着当代精神病学中的精神病理学尺寸组织的越来越大。众多精神障碍和精神病理学措施的数据驱动(即,因子模型为基础的)模型为心理病理学的跨诊断普通因子模型提供了稳健的实证支持。一般性精神病理学或“P”因素反映了精神病理学所有症状的常见变异,以及低于高精神病理学严重程度,从而跨越不同的精神障碍类别和/或症状(即,包括作为经验的输入的症状造型)。这种共同的变化与大多数经典精神障碍类别中通常观察到的高分子率一致。目前的方法工作现在正在解决有关“P”因子和合理机制的实证定义的重要问题,这引起了精神疾病(或症状)指标中观察到的相互关系(见Watts等,2020)。随着我们开始在临床实践中综合尺寸症状措施,重要的是考虑尺寸测量的构建体的重要性,以及跨越开发和跨处治疗的轨迹。这些证据将支持以危险的境内识别儿童和青年的循证方法,并将告知预防和干预措施的时间和性质。

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