Computer-aided design/computer-aided manufacturing (CAD/CAM) restorative materials have been widely used owing to a number of advantages, including stable quality of the materials, lower costs, and time-saving factors. Resin-based CAD/CAM materials for definitive restorations are classified into two groups: dispersed nanoparticle-filled composite resin and polymer-infiltrated-ceramic-network materials. Resin-based CAD/CAM materials have been applied to single crown restorations as a monolithic structure for the posterior region. In addition, resin-based CAD/CAM restorations have been applied recently for the anterior area. This literature review summarizes clinical outcomes, such as survival rates and clinical complications of single crown restorations fabricated with resin-based CAD/CAM materials.
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