Short-term influence of garlic supplementation therapy on oxidative stress markers following military physical activity: A preliminary study

摘要

The present study aimed to investigate the short-term influence of garlic supplementation on oxidative stress markers following military physical activity among military women. Twenty women were randomly assigned to two groups of (1) placebo (control), and (2) garlic extract supplement (experimental) along with a physical activity program. The women in the experimental group took garlic extract supplement daily for 14 days. The control group received a placebo containing 500 mg dextrose in a randomised double-blind placebo-controlled design. Blood samples were collected and analysed for plasma Malondialdehyde (MDA) and 8-hydroxy-2- deoxyguanosine (8-OHdG) before the program and 14 days after. The results showed that military physical activity caused a significant increase in 8-OHdG and MDA (p=0.001). Hence a significant difference was found between the placebo and supplement groups in MDA (p=0.001) and 8-OHdG (p=0.001) after exercise. It was concluded that although garlic extract could not prevent oxidative stress, it could attenuate the detrimental effects of oxidative stress among military people during physical activity.