IntroductionSeizures beginning in the adult life require special attention as regards to their etiology because these are likelyto be due to an identifiable cause. Understanding the trend in prevalence of various etiology of seizure will helpin formulation of diagnostic protocol and might help to reduce the cost of investigations. In this retrospectivestudy, we, therefore, aimed to assess etiology and clinical profile of adult onset seizures.MethodsThis was a retrospective study done at Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal.We included patients of both sexes and age 18 years old admitted to neurology ward with seizure disorderand excluded the patients who suffered from unprovoked seizure and epilepsy. Our study variables includeddemographic profile of patients, co-morbidities, clinical features, laboratory investigation, neuro-imaging, EEGand drugs.ResultsAmong 26 patients, 3 (11.5%) had hyponatremia, 2(7.7%) had intra-cranial space occupying lesion, 12(46.2%) hadneurocysticercosis (NCC), 1 (3.8%) had opioid withdrawal, 1 (3.8%) had alcohol withdrawal, 1 (3.8%) had stroke,1 (3.8%) tuberculoma and in 5 (19.2%) patients no underlying cause was found.ConclusionNCC was the most common cause of seizure disorders among adults. Even after huge development in laboratory,neuroimaging and neurophysiology testing, in as much as 19.2% patients, no etiology could be found.
展开▼
