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Should We Be Afraid Of Neuroendocrine Appendix Tumors?

机译:我们应该害怕神经内分泌阑尾肿瘤吗?

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Introduction: Appendix neoplasms are rarely seen and usually detected by chance after appendectomy. Carcinoid tumors, also called neuroendocrine tumors, make up more than 50% of appendix tumors. Since the diagnosis is usually made as a result of examination of postoperative pathology specimens, patients should be followed up well after appendectomy. Material and Method: 820 appendectomies performed between 2016 and 2020 in Eskisehir Osmangazi University General Surgery Clinic were examined and the patients whose pathology results were appearing as appendix neoplasm were retrospectively analyzed. Results: Neoplastic lesions were detected in 22 of 820 patients. The most common tumoral lesions in the appendix are neuroendocrine tumors and were seen in 8 patients (0.9%) in our series. The average age of patients is 44.75. It was determined that 6 of the patients were male and 2 were female. The average tumor diameter was found to be 4.9 mm. Discussion: Among the appendix malignant tumors, neuroendocrine tumors are the most common. Apart from this, although rare, goblet cell carcinoma, lymphoma, mucocele, primary adenocarcinoma and mucinous cystadenocarcinoma are also seen. In our study, the incidence of neuroendocrine tumors in patients with appendectomy was 0.9%. In the literature, the rates on this issue range from 0.3% to 0.9%. In our study, the average age of patients with neuroendocrine tumors was determined to be 44.75 and is consistent with the literature. Appendix neuroendocrine tumors rarely metastasize. Carcinoid syndrome due to appendix carcinoid tumor is rare and is often associated with liver metastasis. Although serosal and intramural lymphatic invasion, tumors smaller than 2 cm in diameter can be treated with appendectomy and mesoapendix resection. Conclusion: Appendix neoplasms are generally diagnosed after examination of pathology specimens after appendectomy. Although their prognosis is good, they should be followed closely since the presence of synchronous and metachronous tumor is high.
机译:简介:附录肿瘤很少见,通常在阑尾切除后偶然检测到。类癌肿瘤,也称为神经内分泌肿瘤,占阑尾肿瘤的50%以上。由于诊断通常由于术后病理标本的检查而制作,因此患者应在阑尾切除后进行良好。材料和方法:在2016年至2020年间在Eskisehir奥斯蒙扎尼大学之间进行的820份阑尾切除术,并回顾性分析了作为附录肿瘤出现的病理结果出现的患者。结果:820例患者中检测到肿瘤病变。附录中最常见的肿瘤病变是神经内分泌肿瘤,在我们的系列中有8名患者(0.9%)。患者的平均年龄是44.75。确定6名患者是男性,2例是女性。发现平均肿瘤直径为4.9mm。讨论:在附录恶性肿瘤中,神经内分泌肿瘤是最常见的。除此之外,还可以看到罕见,脚耳细胞癌,淋巴瘤,粘膜,原发性腺癌和粘液性膀胱瘤细胞瘤。在我们的研究中,阑尾切除术患者的神经内分泌肿瘤的发病率为0.9%。在文献中,这个问题的税率范围为0.3%至0.9%。在我们的研究中,确定神经内分泌肿瘤患者的平均年龄是44.75,与文献一致。附录神经内分泌肿瘤很少转移。由于附录类癌肿瘤引起的类癌综合征是罕见的,通常与肝转移相关。虽然血清和障碍淋巴侵入,但直径小于2厘米的肿瘤可以用阑尾切除术和Mesoapendix切除治疗。结论:阑尾肿瘤通常在阑尾切除后检测病理标本后诊断。虽然他们的预后很好,但由于存在同步和相距肿瘤的存在,因此应紧紧遵循。

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