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Intravenous Iron Sucrose Therapy in Anemia with Pregnancy

机译:静脉内铁蔗糖治疗贫血怀孕

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Anemia of pregnancy is most common medical disorder in the developing country, affecting 2 billion population worldwide. In India prevalence is 49.7% of pregnancy contributing to 80% of maternal mortality. Parental iron therapy produces rapid, complete correction of iron deficiency including iron stores. Intravenous iron sucrose therapy has become gold standard in management. It has many advantages over other iron preparations in correction of anemia. AIMS AND OBJECTIVE: Evaluation of hemoglobin improvement, time required, and patient’s compliance after iron sucrose therapy. MATERIAL AND METHODS: Retrospective analysis was done of 264 pregnant women with anemia who were admitted in AL-Zahra Teaching Hospital from May 2015 to August 2019, and were diagnosed as iron deficiency anemia and had received intravenous iron sucrose 200 mg weekly till targeted hemoglobin 10gm was reached. RESULTS: majority of women (54.2%) were in age group of 21-29 years. 66.3% were resident of rural area. Anemia was more common (69.7%) in women with vegetarian diet. 83% 0f patients were multigravida. 48.9% cases were of mild, 44.7% of moderate, and 6.4% of severe anemia. There was initial rise in Hb within a week and rise of 1-2gm Hb per week attaining a targeted Hb. CONCLUSION: Iron sucrose is the best tolerated drug, gives mean Hb rise by 600 mg in all grades of anemia and in maximum periods of 4 weeks. Looking at the patient’s compliance and feasibility this drug has replaced strategy of unnecessary blood transfusions.
机译:妊娠期贫血是发展中国家最常见的医疗障碍,影响了20亿人口全球。印度患病率为妊娠的49.7%导致孕产妇死亡率的80%。父母的铁疗法产生迅速,完全纠正铁缺乏,包括铁商店。静脉注射铁蔗糖治疗已成为管理的黄金标准。在校正贫血中的其他铁制剂中具有许多优点。目的和目的:评估血红蛋白改善,需要时间和患者在铁蔗糖治疗后的依从性。材料和方法:回顾性分析是从2015年5月至2019年5月到2019年5月的Al-Zahra教学医院录取的264名孕妇,并被诊断为缺铁性贫血,并在靶向血红蛋白10GM中接受静脉注射的铁蔗糖200毫克,直至靶向血红蛋白10GM达到了。结果:大多数女性(54.2%)为21-29岁的年龄组。 66.3%是农村地区的居民。贫血更常见(69.7%)素食饮食。 83%的0F患者是多人黄典。 48.9%的病例温和,44.7%的中度,6.4%的严重贫血。一周内的HB初始上升,每周上升1-2GM HB,达到目标HB。结论:铁蔗糖是最佳的耐受药物,在所有等级的贫血中和最长期为4周内,均匀Hb升高600毫克。看着患者的合规性和可行性这种药物已经取代了不必要的输血策略。

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