This study was carried out to investigate the common adjustment challenges freshmen in the University of Cape Coast experience during their first year in school, and the coping strategies they used in response to the adjustment challenges. A mixed model research design was used in carrying out the study. A sample of 355 students made up of 235 males and 120 females was selected through purposive and proportional stratified random sampling techniques. Adapted forms of the Student Adaptation to College Questionnaire (SACQ) developed by Baker and Siryk (1999) and the Ways of Coping Questionnaire (WCQ) developed by Folkman and Lazarus (1988) were used along with a semi-structured interview. Quantitative data was analysed descriptively while qualitative data was analysed thematically. The study found that freshmen in the University of Cape Coast encountered adjustment challenges such as difficulty handling the academic pressure and lack of involvement in social activities. In terms of coping, most respondents adopted Planful Problem Solving strategies which involved planning, concentrating and taking action to resolve issues. It was recommended that university authorities make the timetable of freshmen more flexible to enable them cope with the academic pressure.
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