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The Lebanese left ventricular assist device experience, a success story despite the odds

机译:黎巴嫩左心室辅助设备经验,尽管有可能性,但成功的故事

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摘要

Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients. From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10?years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5?years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303?±?213?days. In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon.
机译:心力衰竭仍然是死亡率和发病率的主要原因。辅助设备保留用于未经其他治疗选择的晚期心力衰竭患者。我们的目标是描述黎巴嫩左心室辅助装置(LVAD)患者的特征和结果。从2010年到2019年12月,78名患者植入了贝鲁特心脏研究所的辅助装置,使用了82个泵。在10岁以后的最新后续岁月后,26名患者死亡(34%)。 24例35例(68%)幸存超过5岁。七名患者仅在一个月的手术中死亡。一年死亡率为19%(15名患者)。早期死亡率的主要原因是感染,而脑血管事故CVA是晚期死亡率的主要原因。泵血栓形成发生在12%的病例中。最严重的长期并发症是出血性CVA。只有七名患者(9%)接受心脏移植,在移植之前的平均支撑时间为1303?±213?天。在这份手稿中,我们报告了黎巴嫩最大的LVAD患者患者的特征和结果。一年的生存率为81%。这些调查结果与国际注册管理机构相当,除了心脏移植率。应在黎巴嫩鼓励有机捐赠的更多努力。

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