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Predicting Health with Function ‐? How Can Biomechanics “Ride the Tiger”?

机译:用功能预测健康 - ?生物力学如何“骑老虎”?

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Gait speed is a well-established surrogate endpoint to manyclinical studies and has, specifically in geriatric evaluations,been shown to correlate with various medical compromisedconditions and even patient survival.1,2 In a recent publication,Piau et al. could identify a decline in walking speed3 months prior to actually suffering from a fall event showingthe high relevance of walking speed as indicator for functionalimpairment or even impending injuries.3 In the elderly,each 10th fall results in a major trauma such as a fracture.4Such observations illustrate the significance of changes in gaitspeed as indicator for progression of neuro-musculoskeletaldegeneration. While gait speed is an indicator, the underlyingbiomechanical mechanisms that relate such speed toneuro-musculoskeletal degeneration remain elusive andhow gait speed indirectly or eventually directly affects overallpatient conditions and survival remains unknown.
机译:步态速度是一个完善的代理终点,对多临床研究,特别是在老年评估中,已被证明与各种医疗危机条件相关,甚至在最近出版物中甚至患者存活率,Piau等。可以确定在实际遭受秋季事件之前的步行速度3个月下降,落下的步行速度作为功能效果甚至常驻损伤的指示甚至在老年人处于临时伤害.3中,每个第10个都会导致一个主要的创伤,如骨折.4such观察结果说明了Gaitspeed变化作为神经肌肉骨骼骨骼进展的指标的重要性。虽然步态速度是一个指示器,但涉及这种速度Toneuro-Musculoskeletal变性的基础工骨性机制仍然是难以捉摸的和热带步态速度,或最终直接影响总体障碍条件,生存仍然未知。

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