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Effect of protective glasses on radiation dose to eye lenses during whole breast irradiation

机译:保护玻璃对整个乳房辐射期间辐射剂量对眼镜的影响

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Objectives The efficacy of radiotherapy for breast cancer has greatly improved owing to better irradiation methods. Radiotherapy aims to deliver therapeutic doses to predetermined target volumes while sparing surrounding healthy tissues. However, there are few reports on radiation exposure to eye lenses, and the recommended exposure limits to ocular lens have been substantially reduced in recent years. This study aimed to investigate the amount of radiation exposure to eye lenses using optically stimulated luminescence dosimeters (OSLDs) and determine whether wearing special protective devices to protect the eyes, as an organ at risk, during whole breast irradiation, is necessary. Methods This experiment used OSLDs on water‐equivalent phantom to measure the change in scattered radiation dose due to the difference of irradiation field while using 4‐ and 6‐MV photons of TrueBeam linear accelerator. Using a total treatment dose of 50?Gy, a target was positioned to approximate the breast, and a plan was formulated to deliver 2?Gy per treatment by tangential irradiation. The mean (SD) irradiation dose at the lens position outside the irradiation field was reported. Results The scattered radiation dose outside the irradiation field was more affected by the irradiation field size than by the radiation energy. The out‐of‐field irradiation dose with a larger field of view was higher than that with a smaller field of view. The use of 0.07‐ and 0.83‐mm‐thick lead shield protective glasses reduced the radiation dose by 56.1% ( P ?.001) and 55.6% ( P ?.001), respectively. Conclusions In this experimental model, the amount of radiation the eye was exposed to during whole breast irradiation was determined by the distance of the eye from the radiation field edge and by wearing protective glasses. In clinical practice, the protection offered by eyeglasses may reduce the risk of long‐term side effects and allow the use of higher intensive radiotherapy.
机译:由于更好的照射方法,目的,放疗放疗对乳腺癌的疗效极大地改善。放射疗法旨在将治疗剂量递送至预定的目标体积,同时备受围绕健康组织。然而,近年来,辐射暴露于眼镜的辐射暴露的报告甚至辐射镜片的推荐限制大幅减少。本研究旨在使用光学刺激的发光剂量计(OSLD)来研究眼镜的辐射暴露量,并确定是否佩戴特殊的防护装置以保护眼睛,作为风险的器官,在整个乳房辐射期间是必要的。方法本实验使用了欧扣对水当量模拟,以测量散射辐射剂量因照射场的差异而采用真空线性加速器的4-和6-MV光子而导致的散射辐射剂量。使用总处理剂量为50?GY,定位靶标以近似乳房,并配制一个计划以通过切向照射每处理2μm。报道了辐照场外透镜位置处的平均值(SD)辐射剂量。结果辐射场外的散射辐射剂量受到照射场大小的影响而不是通过辐射能量。具有较大视野的现场外辐射剂量高于具有较小视野的辐射剂量。使用0.07-和0.83毫米厚的引线屏蔽防护眼镜,分别将辐射剂量降低56.1%(P <→001)和55.6%(P <→001)。结论在该实验模型中,眼睛在整个乳房照射期间暴露的辐射量由眼睛从辐射场边缘的距离和穿着防护眼镜确定。在临床实践中,眼镜提供的保护可能会降低长期副作用的风险,并允许使用更高的密集放射治疗。

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