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Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer

机译:使用双喷嘴热塑​​性3D打印机制造具有多个组织的小儿躯干幻像

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Purpose To demonstrate an on‐demand and nearly automatic method for fabricating tissue‐equivalent physical anthropomorphic phantoms for imaging and dosimetry applications using a dual nozzle thermoplastic three‐dimensional (3D) printer and two types of plastic. Methods Two 3D printing plastics were investigated: (a) Normal polylactic acid (PLA) as a soft tissue simulant and (b) Iron PLA (PLA‐Fe), a composite of PLA and iron powder, as a bone simulant. The plastics and geometry of a 1‐yr‐old computational phantom were combined with a dual extrusion 3D printer to fabricate an anthropomorphic imaging phantom. The volumetric fill density of the 3D‐printed parts was varied to approximate tissues of different radiographic density using a calibration curve relating the printer infill density setting to measured CT number. As a demonstration of our method we printed a 10?cm axial cross‐section of the computational phantom’s torso at full scale. We imaged the phantom on a CT scanner and compared HU values to those of a 1‐yr‐old patient and a commercial 5‐yr‐old physical phantom. Results The phantom was printed in six parts over the course of a week. The printed phantom included 30 separate anatomical regions including soft tissue remainder, lungs (left and right), heart, esophagus, rib cage (left and right ribs 1 to 10), clavicles (left and right), scapulae (left and right), thoracic vertebrae (one solid object defining thoracic vertebrae T1 to T9). CT scanning of the phantom showed five distinct radiographic regions (heart, lung, soft tissue remainder, bone, and air cavity) despite using only two types of plastic. The 3D‐printed phantom demonstrated excellent similarity to commercially available phantoms, although key limitations in the printer and printing materials leave opportunity for improvement. Conclusion Patient‐specific anthropomorphic phantoms can be 3D printed and assembled in sections for imaging and dosimetry applications. Such phantoms will be useful for dose verification purposes when commercial phantoms are unavailable for purchase in the specific anatomies of interest.
机译:目的,用于展示使用双喷嘴热塑​​性三维(3D)打印机和两种类型的塑料制造用于制造组织等同物理拟蒽型模拟的组织当量的物理拟人偶像模拟和剂量测定应用的点播和几乎自动方法。方法研究了两种3D打印塑料:(a)正常聚乳酸(PLA)作为软组织模拟剂和(b)铁PLA(PLA-Fe),PLA和铁粉的复合材料,作为骨模拟剂。 1 yr旧的计算模型的塑料和几何形状与双挤出3D打印机相结合,以制造拟人的成像模拟。使用将打印机填充密度设置相关的校准曲线与测量的CT编号相比,3D印刷部件的体积填充密度变化为不同的射线照相密度的近似组织。作为我们的方法的演示,我们以满量程打印了一个10?CM轴向横截面的计算幻像的躯干。我们在CT扫描仪上映像,并将HU值与1岁患者和商业5年龄的物理幻影进行了比较。结果幻影在一周内六个部分打印。印刷的幻影包括30个单独的解剖区域,包括软组织余量,肺(左右),心脏,食道,肋骨(左肋1至10),克拉夫汇(左右),肩胛骨(左右),胸椎(一个固体物体定义胸椎T1至T9)。尽管仅使用两种类型的塑料,CT扫描幻像显示了五个不同的放射线区域(心脏,肺,软组织余量,骨骼和空气腔)。 3D印刷的幻影与商业上可获得的幻像表现出优异的相似性,尽管打印机和印刷材料的主要限制留下了改进的机会。结论患者特异性拟方针模拟可以是用于成像和剂量测定应用的部分印刷和组装的3D。当商业幽灵在特定解剖学中不可用时,这种幽灵对于剂量验证目的是有用的。

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