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A fuzzy optimization approach to strategic organ transplantation network design problem: A real case study

机译:战略器官移植网络设计问题的模糊优化方法:真正的案例研究

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Designing an efficient supply chain for organ transplant networks which is intimately related to humans’ life plays a primary role in improving the network’s performance. This research is focused on proposing a new multi-period location-allocation modeling approach to make appropriate strategic decisions for designing organ transplant networks under supply and budget uncertainties. To serve this purpose, a bi-objective possibilistic programming model is formulated the aim of which is to maximize network responsiveness and minimize the total cost. A fuzzy goal programming approach is adopted to solve multiple objective function models and control their deviations from the corresponding aspiration levels. As an important contribution of this study, the chance of success of transplantation processes is taken into consideration by proposing appropriate utility functions according to transportation criteria. Moreover, for the purpose of coping with the inherent uncertainty of the input parameters, a possibilistic programming model based on Me measure converted to three optimistic, realistic and pessimistic models is developed. Three new formulations have also been developed to tackle equality chance constraints. Finally, the optimal solutions of the developed models are analyzed through conducting a real case study in Iran. According to the results, for the considered organ transplant network, the possibilistic programming model based on the realistic measure is better than the optimistic and pessimistic measure in most confidence levels.
机译:设计与人类生活密切相关的器官移植网络的有效供应链在提高网络的性能方面发挥着主要作用。本研究专注于提出新的多时期位置分配建模方法,以对供应和预算不确定因素设计器官移植网络进行适当的战略决策。为满足此目的,配制了双目标可能的编程模型,其目的是最大化网络响应性并最小化总成本。采用模糊的目标编程方法来解决多种目标函数模型,并控制与相应抽吸水平的偏差。作为本研究的重要贡献,通过根据运输标准提出适当的效用功能,考虑移植过程成功的机会。此外,为了应对输入参数的固有不确定性,开发了一种基于ME测量的可能性编程模型转换为三种乐观,现实和悲观模型。还开发了三种新的配方来解决平等机会限制。最后,通过在伊朗进行真正的案例研究,分析了开发模型的最佳解决方案。根据结果​​,对于考虑器官移植网络,基于现实措施的可能性编程模型优于大多数置信水平的乐观和悲观措施。

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