Objectives: To determine the frequency of elevated plasma homocysteine (Hcy) levels among type 2 diabetes mellitus (T2DM) patients. Study Design: Cross sectional study. Setting: Department of Medicine, Abbasi Shaheed Hospital, Karachi. Period: From 28 September 2012 to 26 March 2015. Material & Methods: Type 2 Diabetic patients fulfilling inclusion criteria were enrolled. Patients with conditions known to cause altered homocysteine levels were excluded. Patients’ HbA1c and fasting serum homocysteine levels were obtained. Level 15 μmol/L was labeled as elevated. Data was collected with the help of Performa. Data was analyzed using SPSS version 21. Results: (90) ninety patients were enrolled in this study during study period with mean age of 61.5±7.3 years. Of (90) ninety patients, 45 (50%) were male and 45 (50%) were female with male to female ratio of 1:1. Mean duration of diabetes was 6.9±1.7 years. 40 (44.44%) cases were of controlled diabetes and 43 (47.7%) were on treatment. Of 90 patients 36 (40%) patients had Homocysteinemia. Homocysteine levels were found to be significantly raised in males 51.1% v/s 28.8% (p60 years of age) 55.5% v/s 16.6% (p 7 years, 59.2% v/s 17%(p60 years of age, non-compliant diabetics, have long duration diabetes, and uncontrolled disease.
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机译：目的：为了确定升高的血浆高半胱氨酸（Hcy）水平等级的2型糖尿病（T2DM）患者中的频率。研究设计：横断面研究。设置：医药，阿巴斯·沙希德医院，卡拉奇系。期间：从2012年9月3月28日至26日2015年材料与方法：2型履行纳入标准的糖尿病患者参加。与已知造成改变同型半胱氨酸水平条件的患者被排除。得到患者的HbA1c和空腹血清同型半胱氨酸水平。水平> 15微摩尔/ L标记为升高。数据与的Performa的帮助下收集。 （90），90例在这项研究中研究期间61.5±7.3岁，平均年龄入选：使用SPSS软件版本21.结果分析数据。 （90）90例患者中，45（50％）为男性，45（50％）为女性与男性对女性的比为1：1。糖尿病的平均时间为6.9±1.7年。 40（44.44％）例控制糖尿病和43（47.7％）是在治疗。 90名患者的36（40％）患者具有同型半胱氨酸。被发现的高半胱氨酸水平，以在男性被显著升高51.1％V / S 28.8％（P60岁）55.5％V / S 16.6％（第7页年，59.2％V / S 17％（P60岁以下，非兼容糖尿病患者，有持续时间长糖尿病和失控的疾病。
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