Background/Aims:Frailty is mainly due to an age-related decrease in the physiological reserves needed to maintain biological homeostasis, but it can also occur as a result of chronic diseases. The purpose of this study was to identify illnesses associated with frailty in Korean community-dwelling older adults.Methods:This was a cross-sectional study that included 2,936 older adults aged between 70 and 84 years who had completed both interviews and physical function assessments for the Korean Frailty and Aging Cohort Study. Current illnesses diagnosed by physicians were included in the analysis. The definition of frailty was derived from the Fried frailty phenotype.Results:The prevalence of hypertension, diabetes mellitus (DM), arthritis, osteoporosis, urinary incontinence, and lung disease (including asthma, chronic obstructive pulmonary disease, and chronic bronchitis) was higher in the frail group (p 0.05). After adjusting for age, sex, physical activity, alcohol, smoking, education, and presence of a spouse, the odds ratios for DM and urinary incontinence in frailty were 1.51 (95% confidence interval [CI], 1.10 to 2.01; p = 0.01) and 1.88 (95% CI, 1.11 to 3.18; p = 0.02).Conclusions:In Korean community-dwelling older adults, DM and urinary incontinence were associated with frailty after adjusting for various factors. In the future, the list of comorbid diseases that are appropriate for Korean population- specific frailty assessment should be inventoried.
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机译：背景/目标：脆弱主要是由于维持生物稳态所需的生理储备的年龄有关的减少，但也可能由于慢性疾病而发生。本研究的目的是识别与韩国社区住宅老年人的脆弱相关的疾病。方法：这是一个横断面研究，其中包括2,936名年龄在70到84岁之间的年龄，完成了两个面试和物理职能评估韩国体力和老化的队列研究。医生诊断的目前疾病被列入分析。脆弱的定义是源自油炸的脆弱表型。结果：高血压，糖尿病（DM），关节炎，骨质疏松症，尿失禁和肺病（包括哮喘，慢性阻塞性肺病和慢性支气管炎）的患病率较高在Freail组（P <0.05）。调整年龄，性别，身体活动，酒精，吸烟，教育和存在，脆弱的DM和尿失禁的差距为1.51（95％置信区间[CI]，1.10至2.01; P = 0.01 ）和1.88（95％CI，1.11至3.18; P = 0.02）。CONCLUSIONS：在韩国社区居住的老年人，调整各种因素后，DM和尿失禁有关的脆弱。将来，应清点适合韩国人口特异性脆弱评估的合并疾病清单。
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