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Prostate cancer trajectory-map: clinical decision support system for prognosis management of radical prostatectomy

机译:前列腺癌轨迹 - 地图:自由基前列腺切除术预后管理的临床决策支持系统

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PurposeProstate cancer has a low mortality rate and requires persistent treatment; however, treatment decisions are challenging. Because prostate cancer is complex, the outcomes warrant thorough follow-up evaluation for appropriate treatment. Electronic health records (EHRs) do not present intuitive information. This study aimed to develop a Clinical Decision Support System (CDSS) for prognosis management of radical prostatectomy.MethodsWe used data from 5,199 prostate cancer patients from three hospitals’ EHRs in South Korea, comprising laboratory results, surgery, medication, and radiation therapy. We used open source R for data preprocessing and development of web-based visualization system. We also used R for automatic calculation functionalities of two factors to visualize the data, e.g., Prostate-Specific Antigen Doubling Time (PSADT), and four Biochemical Recurrence (BCR) definitions: American Society of Therapeutic Radiology and Oncology (ASTRO), Phoenix, consecutive PSA?>?0.2?ng/mL, and PSA?>?0.2?ng/mL.ResultsWe developed the Prostate Cancer Trajectory Map (PCT-Map) as a CDSS for intuitive visualization of serial data of PSA, testosterone, surgery, medication, radiation therapy, BCR, and PSADT.ConclusionsThe PCT-Map comprises functionalities for BCR and PSADT and calculates and visualizes the newly added patient data automatically in a PCT-Map data format, thus optimizing the visualization of patient data and allowing clinicians to promptly access patient data to decide the appropriate treatment.
机译:目的癌症的死亡率低,需要持续治疗;然而,治疗决策是具有挑战性的。由于前列腺癌是复杂的,结果是为了适当治疗的彻底进行后续评估。电子健康记录(EHRS)不提供直观的信息。本研究旨在开发临床决策支持系统(CDS),用于激进前列腺切除术的预后管理。韩国三个医院的ehrs的5,199名前列腺癌患者的数据,包括实验室结果,手术,药物和放射治疗。我们使用了基于Web的可视化系统的数据预处理和开发的开源R.我们还使用R进行自动计算功能,以便可视化数据,例如,前列腺特异性抗原倍增时间(Psadt)和四种生物化学复发(BCR)定义:美国治疗放射学和肿瘤学会(Astro),凤凰,连续PSA?>?0.2?Ng / ml和PSA?>?0.2?ng / ml.Resultwe开发了前列腺癌轨迹地图(PCT-MAP)作为表现为PSA,睾酮,手术的序列数据的直观可视化的CDS,组织,放射治疗,BCR和PSADT。PCT-MAP包括BCR和PSADT的功能,并在PCT地图数据格式中自动计算和可视化新增的患者数据,从而优化患者数据的可视化并允许临床医生及时允许临床医生访问患者数据以决定适当的治疗方法。

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