DCLAK11 treatment induces apoptosis in non‐small cell lung cancer cells by inhibiting the mitochondrial apoptosis pathway

摘要

Objective DCLAK11 is a novel small molecule tyrosine kinase inhibitor with remarkable effects on cell proliferation and apoptosis in non‐small cell lung cancer cells. Therefore, it is necessary to determine the molecular mechanisms of action of this compound. In this study, we investigated the antitumor effect that DCLAK11 exerts through inhibition of the mitochondrial apoptosis pathway.