Unrestricted use of anticoagulants has resulted in rodents developing resistance tothem. This has caused a series of problems regarding reduction in rodent populations, whichhas further implicated great economic losses and a serious threat to the health of peopleand domestic animals. The popular global trend currently is to control rodent populationsby applying the least possible amounts of chemicals, which on the other hand impliesthat several coactive alterantive measures need to be applied in an eff ort to reduce rodentnumbers to an acceptable economic level. On the other hand, knowledge of the geneticstructure of rodent populations has become an important set of information desirable tohave before setting off to apply rodenticides in practice, so as to prevent ineff ective useof rodenticides and prevent further spreading of resistant rodent populations. The latesttrend of using combinations of low-dose anticoagulant baits requires further research astheir eff ects on susceptible populations are known but their impact on resistant animals isstill not clear.
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