We intensively read the recent review, “Is Epidural Injection of Sodium Chloride Solution a True Placebo or an Active Control Agent? A Systematic Review and Meta-Analysis” written by Manchikanti L et al (1). It was described in the article that epidural sodium chloride should not be considered as a placebo and it is effective in the treatment of low back and lower extremity pain. When the efficiencies of epidural local anesthetic and epidural local anesthetic combined with steroid injection were compared, no difference was found between their efficacy.
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