Objective: To determine the frequency of hyponatremia in patients taking Sodium Picosulfate Solution (SPS) solution for bowel preparation prior to colonoscopy and to compare serum sodium levels before and after SPS. Methods: This interventional study was conducted at Dr. Ruth K. M. Pfau, Civil Hospital Karachi between June 2019 to November 2019. Patients undergoing colonoscopy were included in the study. All patients were given SPS. Two samples of blood for electrolytes were taken, one 30 minutes before taking SPS solution and another 30 minutes before colonoscopy. Paired sample t-test was used to determine the difference between serum sodium level before taking the colonoscopy solution and serum sodium level before colonoscopy. Results: Fifty- four patients fulfilling inclusion criteria were included. Out of the 54 patients 28 (51.9%) were males and 26 (48.1%) were females. Mean sodium levels before taking colonoscopy solution was 139.7±3.5 mEq/L and mean sodium level before colonoscopy was 138.9±3.8 mEq/L. The difference between serum sodium level before taking SPS colonoscopy solution and before colonoscopy was found to be statistically insignificant (t (53) = 1.308; p = 0.196). Conclusion: No serious adverse effects were reported in any of our patients. There was no significant difference in the serum sodium level of patients undergoing colonoscopy before taking SPS bowel preparation solution and serum sodium level before colonoscopy. doi: https://doi.org/10.12669/pjms.36.7.2376 How to cite this:Rasheed T, Alvi H, Shaikh MA, Ali FS, Zuberi BF, Subhan W. Frequency of hyponatremia caused by sodium picosulfate solution when used as a bowel cleansing agent for colonoscopy. Pak J Med Sci. 2020;36(7):---------. doi: https://doi.org/10.12669/pjms.36.7.2376 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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机译：目的：测定患者患者患者患者的低钠血症溶液（SPS）溶液在结肠镜检查之前进行肠血症的频率，并在SPS之前和后比较血清钠水平。方法：该介入研究是在2019年6月至2019年11月的公民医院卡拉奇·卢温K.·米博士·普氏博士。患有结肠镜检查的患者。所有患者都被给予了SPS。采用两种电解质样品，在结肠镜检查前30分钟后，在进行SPS溶液前30分钟。配对样品T检验用于确定在结肠镜检查前进行结肠镜检查溶液和结肠镜检查的血清钠水平之间的差异。结果：包括符合纳入标准的五十四名患者。在54名患者中，28例（51.9％）是男性，26例（48.1％）是女性。在结肠镜检查前的平均钠水平为结肠镜检查为139.7±3.5meq / L，并且在结肠镜检查之前平均钠水平为138.9±3.8 meq / L.发现SPS结肠镜检查溶液和结肠镜检查前血清钠水平的差异是统计学上微不足道的（T（53）= 1.308; p = 0.196）。结论：我们的任何患者都没有报告严重的不利影响。在结肠镜检查前服用SPS肠道制备溶液和血清钠水平之前，在结肠镜检查之前没有显着差异。 DOI：https://doi.org/10.12669/pjms.36.7.2376如何引用这一点：Rasheed T，Alvi H，Shaikh Ma，Ali Fs，Zuberi BF，Subhan W.使用时硫酸钠溶液引起的低钠血症频率作为结肠镜检查的肠道清洁剂。 Pak J Med Sci。 2020; 36（7）：---------。 DOI：https://doi.org/10.12669/pjms.36.7.2376这是一个在Creative Commons归因许可（http://creativecommons.org/licenses/by/3.0）下的开放式访问文章，哪些只要正确引用原始工作，允许在任何媒体中不受限制使用，分发和再现。
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