Research on the Correlation of Serum PCT and Plasma?GSN Levels with the Prognosis of Urosepsis Patients

摘要

Objective: To explore the correlation of procalcitonin (PCT) and gelsolin (GSN) with the prognosis ofurosepsis patients.Method: The data of 71 urosepsis patients from March 2015 to April 2019 who were admitted to andtreated in Affiliated Hospital of Hebei University were analyzed and compared with those of 92 healthypersons. Serum PCT and plasma GSN levels at different times after treatment were detected. According toprognosis, patients were classified into the good prognosis group or the poor prognosis group. The serumPCT and plasma GSN levels of both groups were compared.Result: The serum PCT level of the urosepsis group on the 1st, 3rd, 5th and 7th days was obviously higherthan that of the control group (P0.05). The plasma GSN levels of the urosepsis group on the 1st, 3rd, 5thand 7th days were obviously lower than those of the control group (P0.05).The serum PCT level of the poorprognosis group on the 1st, 3rd, 5th and 7th days was obviously higher than that of the good prognosis group(P0.05). The plasma GSN level of the poor prognosis group on the 1st, 3rd, 5th and 7th days was obviouslylower than that of the good prognosis group (P0.05). PCT was an independent risk factor influencing theprognosis of urosepsis patients and that GSN was a protective factor (P0.05).Conclusion: The serum PCT and plasma GSN levels can accurately predict the severity and prognosis ofurosepsis patients and reflect the disease state of early urosepsis patients. High PCT levels and low GSNlevels indicate poor prognosis, and clinicians should consider these values.