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Bacteriological Profile of Acute Respiratory Infections in Children: About a Prospective Study at the Albert Royer Hospital in Dakar

机译:儿童急性呼吸道感染的细菌概况:关于达喀尔莱伯特莱科医院的前瞻性研究

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Introduction: Acute Respiratory Infections (ARI) is a global public health priority. It is the leading cause of childhood morbidity and mortality, especially in developing countries. The main objective of this work was to look mainly at the bacteriological aspects of ARI in children in Senegalese hospitals. Methodology: We have been conducted a prospective descriptive mono-centric study over a period of one year (from July 1, 2017 to June 30, 2018) at the Albert Royer National child hospital in Dakar. A multiplex PCR (protein chain reaction) has been performed on nasopharyngeal swabs taken from all patients. This technique (viral RNA transcribed into DNA, then the DNA of the different pathogens is simultaneously amplified in the same tube by PCR Fast-tract ~(&reg) , multiplex). Results: During the study period, 109 patients were included. The hospital prevalence of acute respiratory infections was 3.7%. The mean age was 23.7 months with extremes between 1 month and 144 months. Peaks of consultations were found in the months of August, March and April with 22%, 15.6% and 12.8% respectively. Fever, respiratory distress and pulmonary condensation syndrome were the main signs found in our patients. Bacteriology was positive in 82.6% of samples and the most frequently found bacteria were Streptococcus pneumoniae in 38.5%, Haemophilus influenza b in 32.1% and Moraxella catarrhalis in 25.7%. Pneumonia was the main diagnosis, found in 61 cases, a prevalence of 59.9%. The average length of hospitalization was 10 days. Lethality was 1.8% or 2 cases. Conclusion: Acute Respiratory Infections in children still remains a public health problem in developing countries; children under 5 years of age are the most affected hence the need to strengthen ARI control programs. The identification of germs is indispensable in treatment and epidemiological surveillance in our regions.
机译:简介:急性呼吸道感染(ARI)是全球公共卫生优先权。这是儿童发病率和死亡率的主要原因,特别是在发展中国家。这项工作的主要目标是主要看着塞内加尔医院的儿童Ari的细菌方面。 方法论:我们已经在达喀尔·阿尔伯特·罗伊师全国儿童医院(2018年7月30日至2018年6月30日至2018年6月30日)进行了一项潜在的描述性单元学研究。已经对来自所有患者的鼻咽拭子进行了多重PCR(蛋白链反应)。这种技术(转录到DNA中的病毒RNA,然后通过PCR快速〜(&reg),多重在相同管中同时扩增不同病原体的DNA。 结果:在研究期间,包括109名患者。急性呼吸道感染的医院患病率为3.7%。平均年龄为23.7个月,极端为1个月和144个月。 8月,3月和4月的几个月内发现了磋商峰,分别为22%,15.6%和12.8%。发烧,呼吸窘迫和肺结乳综合征是我们患者的主要标志。在82.6%的样品中,细菌学是阳性的,并且最常发现的细菌在38.5%的38.5%中肺炎链球菌肺炎链球菌,其中在32.1%和 moraxella catarrhalis中的25.7%。肺炎是主要诊断,发现在61例,患病率为59.9%。平均住院时间为10天。致命性为1.8%或2例。 结论:儿童急性呼吸道感染仍然是发展中国家的公共卫生问题; 5岁以下的儿童受到影响最大的,因此需要加强ARI控制计划。我们地区的治疗和流行病学监测是必不可少的。

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