Introduction: Spina bifida is the most common neural tube defect. Uterine prolapse is an exceptional presentation of its complications. We aim to describe the clinical and progressive features of uterine prolapse in a newborn baby with spina bifida. Observation: 19-day-old newborn. Admitted for spina bifida. The clinical examination showed an anal gaping, the presence of uterovaginal prolapse and bilateral equine varus clubfoot. The particularity was that this prolapse had a spontaneous resolution but appears with screams. We made a compression bandage at the time of resolution. After a 6-month of follow-up, the baby is in good general condition and, there is no recurrence of the prolapse. Conclusion: Uterine prolapse is a rare complication of spina bifida. The main therapeutic component remains the prevention of spina bifida.
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