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Left ventricular thrombus and pulmonary embolism: A case series of thrombosis in COVID‐19 in Thai patients

机译:左心室血栓和肺栓塞:泰国患者Covid-19中的血栓形成血栓形成

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Thrombosis in COVID‐19 is increasingly recognized and is generally associated with a high mortality rate. The key clinical question of this report was whether COVID‐19 could be complicated with cardiac thrombus and pulmonary embolism in Asian population. We demonstrated the case series of thrombosis in Thai patients with confirmed severe acute respiratory syndrome coronavirus 2 infection. One patient had the first case of a large left ventricular thrombus, and three other patients had pulmonary embolism. All patients were male and had low absolute lymphocyte count, while lactate dehydrogenase level and d ‐dimer were markedly elevated, especially at the time when the thrombosis was diagnosed. All patients had severe COVID‐19 with pneumonia. Two patients who needed mechanical ventilation were successfully extubated. After hospitalization for 13‐49?days, pneumonia and thrombosis improved and all of them could be discharged from the hospital. Thrombosis is common in COVID‐19 and could present in both arterial and venous sites even in Asian populations. d ‐dimer is a strong marker to predict thrombosis and could be a prognostic predictor for severity of COVID‐19.
机译:Covid-19中的血栓形成越来越识别,通常与高死亡率相关。本报告的关键临床问题是Covid-19是否可使亚洲人口中的心脏血栓和肺栓塞复杂化。我们证明了泰国患者患者的病例系列血栓形成严重急性呼吸综合征冠状病毒2感染。一名患者有第一种大左心室血栓,另外三名患者具有肺栓塞。所有患者均为雄性并且具有低的绝对淋巴细胞计数,而乳酸脱氢酶水平和D-dimer明显升高,特别是在诊断血栓形成的时候。所有患者患有严重的Covid-19与肺炎。两名需要机械通气的患者成功拔下。住院后13-49?天,肺炎和血栓形成改善,所有这些都可以从医院出院。血栓形成在Covid-19中常见,即使在亚洲人群中也可能存在于动脉和静脉位。 D-dimer是一种强烈的标记,以预测血栓形成,并且可以是Covid-19严重程度的预测预测因子。

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