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Postoperative Thoracic Epidural Analgesia: Adverse Events from a Single-Center Series of 3126 Patients

机译:术后胸腔硬膜外镇痛:单中心系列3126名患者的不良事件

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Purpose: Thoracic epidural analgesia (TEA) has been shown to reduce postsurgical morbidity and mortality; nevertheless, major and minor complications can occur. We report our 10-year experience with TEA and incidence of complications. Patients and Methods: Patients received continuous infusion TEA (0.2% ropivacaine and 2 μg ml ? 1 fentanyl) to control postoperative pain. Every 8 hours, the acute pain service recorded the analgesia regimen and occurrence of side effects. The initial infusion rate was tapered daily in response to improvement in pain symptoms or occurrence of side effects. Results: A total of 3126 patients received TEA. The median age was 65 years (range, 18– 94) and the duration of catheter placement was 3.5 days (range, 2– 8). Three major complications were identified (1:1042): two subarachnoid blocks and one epidural abscess which led to permanent sequela (1:3126). Minor complications were hypotension (4.8%), pruritus (4.4%), accidental catheter removal (3.7%), insertion site inflammation (2.5%), motor weakness (2.0%), postoperative nausea and vomiting (1.8%), catheter disconnection (1.9%), catheter occlusion (0.3%), post-dural puncture headache (0.5%), and catheter fragment retention (0.06%), which were the reasons for a 7.4% rate of early discontinuation of epidural analgesia. No occurrence of epidural hematoma, local anesthetic systemic toxicity, and cardiovascular/respiratory depression was recorded. Conclusion: Postoperative TEA is an advanced technique that poses certain difficulties that can subvert its great potential. While serious complications were rare, minor complications occurred more often and affected the postoperative course negatively. A risk/benefit evaluation of each patient should be done before employing the technique.
机译:目的:已显示胸腔硬膜外镇痛(茶)降低后勤发病率和死亡率;然而,可能发生重大和次要的并发症。我们向我们的茶和并发症发病率报告了10年的经验。患者和方法:患者接受连续输注茶(0.2%Ropivacaine和2μgmLα1芬太尼)以控制术后疼痛。每8小时,急性疼痛服务记录镇痛方案和副作用的发生。初始输注率为每天逐渐变细,以应对疼痛症状或副作用的发生。结果:共有3126名患者接受茶。中位年龄为65岁(范围,18-94),导管放置的持续时间为3.5天(范围,2-8)。鉴定了三个主要并发症(1:1042):两种蛛网膜下腔块和一个硬膜外脓肿,导致永久性后遗症(1:3126)。轻微并发症是低血压(4.8%),瘙痒(4.4%),意外导管去除(3.7%),插入部位炎症(2.5%),电机弱点(2.0%),术后恶心和呕吐(1.8%),导管断开( 1.9%),导管闭塞(0.3%),后刺破头痛(0.5%)和导管片段保留(0.06%),这是硬膜外镇痛早期停药率7.4%的原因。记录了无硬膜外血肿,局部麻醉系统毒性和心血管/呼吸抑郁症的发生。结论:术后茶是一种先进的技术,造成了颠覆其巨大潜力的某些困难。虽然严重的并发症是罕见的,但更常见的并发症较小,并影响术后课程。在采用该技术之前,应进行每个患者的风险/益处评估。

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