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Changing proportions of paucibacillary leprosy cases in global leprosy case notification

机译:在全球麻风病例通知中不断变化比例白细胞麻风病例

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Objectives: Classification of new cases of leprosy into Paucibacillary (PB) or Multibacillary (MB) groups is important as it determines the duration of the treatment regimen, and predicts both complications of leprosy and risk of infection to contacts. Criteria have changed over the past 4 decades. We studied the published global leprosy statistics to reveal any major temporal changes in the proportion of PB cases. Results: Global data published by WHO over the past 40 years demonstrate a continuous decrease in the proportion of newly reported leprosy cases who are classified as paucibacillary (PB) from nearly 80% to around 40%. Independent validation of consistent and accurate classification is lacking. Conclusions: The decrease in PB proportion may be an artefactual, rather than an epidemiological, phenomenon. Whilst it is impossible to be certain, we suspect that a combination of changes in criteria and “overclassifying” to the MB group by field staff is the cause.
机译:目的:对白瓜(Pb)或多绿毛虫(Pb)或多毛虫(MB)组进行新病例的分类是重要的,因为它决定了治疗方案的持续时间,并预测了麻风病的并发症和感染与接触的风险。过去4世纪十年来,标准已发生变化。我们研究了已发表的全球麻风病统计数据,以揭示PB病例比例的任何主要时间变化。结果:过去40岁人发布的全球数据表明,新报告的麻风病病例的比例持续减少,他们被归类为比例(PB)从近80%到约40%。缺乏独立验证一致和准确的分类。结论:Pb比例的减少可能是假期,而不是流行病学现象。虽然不可能确定,但​​我们怀疑标准的变化和“超声处理”的结合通过实地工作人员是MB集团的原因。

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