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Clinical and Neuroimaging Features in a Patient with Non-Ketotic Hyperglycemia

机译:患有非酮症高血糖血症的患者的临床和神经影像学特征

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Hemichorea–hemiballism (HC–HB) is a spectrum of involuntary flinging and flailing, non-patterned, irregular movements involving one side of the body. A rare dysfunction of glucose metabolism leading to a state of non-ketotic hyperglycemia (NKH) is thought to be a cause of these symptoms. In previous case studies, imaging findings have been in the basal ganglia as hyperintense lesions on magnetic resonance imaging (MRI) or hyperdensities on computerized tomography (CT). This case is unique due to abnormal findings in the MRI T2/fluid-attenuated inversion recovery (FLAIR) sequence in areas not previously reported—the thalamus and midbrain/pons. As in other NKH cases, the patient improved both clinically and radiologically. In patients with uncontrolled diabetes and abnormal movements, monitoring of blood glucose is imperative as it can lead to recognition of HC–HB. Other etiologies, including stroke, neoplasm, demyelination, and inflammatory processes, have uncertain prognoses with unfavorable outcomes. The prognosis for NKH is usually favorable, and thus important to identify.
机译:Hemichorea-Hemiballism(HC-HB)是一种涉及身体一侧的非自愿剥落和鞭打,非图案化的不规则运动的光谱。葡萄糖代谢的罕见功能障碍导致非酮症高血糖(NKH)的状态被认为是这些症状的原因。在先前的案例研究中,成像结果已经在基底神经节处于磁共振成像(MRI)或计算机断层扫描(CT)上的高密度的过敏病变。这种情况是由于在前未报道的区域的MRI T2 /流体衰减的反转恢复(Flair)序列中的异常发现是独一无二的。 - 丘脑和中脑/丘脑。与其他NKH病例一样,患者临床和放射性地改善。在患有不受控制的糖尿病和异常运动的患者中,对血糖的监测是必须导致HC-HB的识别。其他病因,包括中风,肿瘤,脱髓鞘和炎症过程,具有不确定的预后具有不利的结果。 NKH的预后通常是有利的,因此重要的是识别。

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