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Pulmonary Fibrosis Due to COVID-19 Pneumonia

机译:Covid-19肺炎引起的肺纤维化

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We read the recent article published in KJR titled “Prediction of the Development of Pulmonary Fibrosis Using Serial Thin-Section CT and Clinical Features in Patients Discharged after Treatment for COVID-19 Pneumonia” with great interest (1). The authors assessed the predictors of pulmonary fibrosis using clinical data and followup chest computed tomography (CT) in patients with coronavirus disease (COVID-19) pneumonia (1). The most common CT findings in COVID-19 pneumonia have been described as ground-glass opacities (GGOs) with or without consolidation, crazy-paving pattern, interstitial thickening, irregular interface, and parenchymal band mainly bilateral and lower lobes predilection with peripheral locations (1). Authors found evidence of fibrosis, i.e., irregular interface and parenchymal bands, in nearly half of the patients on initial CT, and in about 85–92% of the patients on followup CT, and they speculated that interstitial thickening, irregular interface, coarse reticular pattern and parenchymal band, manifesting in the process of the disease, might be predictors of pulmonary fibrosis in patients who recovered from COVID-19 pneumonia (1, 2). An irregular interface and parenchymal band might be two early predictors of pulmonary fibrosis (1). From the clinical point of view, fibrosis can be usually seen in elderly patients with severe clinical conditions, especially in patients with higher level of C-reactive protein and interleukin-6 (1). We are not sure whether the authors detected typical pulmonary fibrosis and honeycomb appearances during the follow-up of COVID-19 patients. We encountered a typical pulmonary fibrosis during the follow-up of one COVID-19 patient, whose initial CT examination showed only GGO. Interstitial thickening, irregular interface, or parenchymal bands were not detected on initial CT examination.
机译:我们阅读了最近在KJR上发布的文章,标题为“使用串行薄缩截面CT和临床特征来预测肺纤维化的肺纤维化的临床特征”,患者在治疗后患者患者患者,伴随着Covid-19肺炎的患者“,具有极大的兴趣(1)。作者评估了使用冠心病病毒疾病(Covid-19)肺炎(1)的临床数据和后续胸部计算机断层扫描(CT)的肺纤维化预测因子。 Covid-19肺炎中最常见的CT发现已被描述为底玻璃不透射率(GGO),具有或不合并,疯狂铺路图案,间质增稠,不规则界面和实质频段主要与外围位置的双侧和低裂片偏移( 1)。作者发现了纤维化,即不规则界面和实质频段的证据,近一半的患者在初始CT上,约85-92%的患者在后续CT上,他们推测了间质增稠,不规则的界面,粗网在疾病过程中表现出的模式和实质频段可能是从Covid-19肺炎(1,2)回收的患者肺纤维化的预测因子。不规则的界面和实质频段可能是肺纤维化的两个早期预测因子(1)。从临床角度来看,纤维化通常可以在老年患者中看到严重的临床病症,尤其是患者患者的C反应蛋白和白细胞介素-6(1)患者。在Covid-19患者的随访期间,我们不确定作者是否检测到典型的肺纤维化和蜂窝状外观。在一个Covid-19患者的随访期间,我们遇到了典型的肺纤维化,其初始CT检查仅显示GGO。在初始CT检查上未检测到间质增稠,不规则界面或实质条带。

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