Stereological analysis of terminal villi, intervillous space and fibrinoid of adolescent placentas and birth weight of newborns

摘要

Aim To determine stereological structural parameters of the parenchymal part of the placenta, placental weight and volume of adolescent pregnant women and their correlation with newborns’ birth weight. Methods This prospective study was conducted on a total of 60 human placentas of term pregnancy, divided into two groups according to the age of pregnant women. Experimental group consisted of 30 placentas of pregnant women aged 13-19 years. Control group consisted of 30 placentas of pregnant women aged 20-35 years. Stereological analysis was performed. Results Volumetric density of terminal villi of adolescent placentas was significantly higher than the one of control group (p 0.0001). The volumetric density of fibrinoid of adolescent placentas was significantly lower than of the control group (p 0.0001). Total volume of terminal villi of adolescent placentas was significantly higher than of the control group (p0.0001). The total volume of fibrinoid of adolescent placentas was significantly lower than of the control group (p0.0001). Newborns of adolescent pregnancies had in average lower birth weight of 439.01 g compared to the newborns of the control group (p 0.00001). Conclusion Adolescent pregnancy affects placental structure, weight and volume. Newborns of adolescent pregnancy have optimal body weight.