Distemper virus is a Morbillivirus (in the family Paramyxoviridae) that can cause contagious disease in dogs. The virus affects the respiratory, digestive, and nervous systems after transmission. In this study, we reported a case of human infection and involvement with the Distemper virus . A 31-year-old man was diagnosed with clinical signs of Distemper in dogs. After serologic tests on saliva, blood samples were taken and RNA was extracted and cDNA synthesis was performed by PCR, and Sequencing was performed on the sample . The results of serological tests on individual saliva and PCR on cDNA from the whole blood sample of the patient and genetic sequencing revealed the results of rejection of viral interference in the tests and accuracy of Distemper virus detection. As the first cause of the disease was in humans . The results of this study revealed human infection and involvement with Distemper virus and the necessity of preventive measures such as specific vaccination against the Distemper virus in the wild and domestic animal community.
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