Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance

摘要

Introduction: The Heart Rate Performance Curve (HRPC) is neither linear nor uniform and related to ß1-adrenoceptor sensitivity. As aging and exercise influence ß1-adrenoceptors we suggested age, sex and performance effects on the HRPC. Aim of the study was to examine the effects of aging on the deflection of the HRPC in maximal incremental cycle ergometer exercise (CE) in a large cohort of healthy subjects. Methods: Heart rate (HR) data of 2980 men (51±15 yrs) and 1944 women (52±14 yrs) were classified into age groups (≤20 up to 80 yrs). We analyzed age and performance (Plow 25%-quartile and Phigh 75%-quartile of age predicted power) effects on HRmax and on the degree (k) and the type (regular downward deflection k0.1, linear -0.1≤k≤0.1 and atypical upward deflection k-0.1) of the HRPC. Results: k-values decreased significantly with age in men and women and were significantly higher in women. Atypical HRPC´s increased by a linear trend from ≤20 to 70 yrs (m) respectively 80 yrs (w) from 10% to 43% (m) and 9% to 30% (w). HRmax of all age groups was lower in Plow and overall number of atypical HRPC´s was 21% (m) and 16% (w) higher compared to Phigh. Conclusion: Aging increased the number of atypical HRPC´s with upward deflection in CE tests, which influences exercise intensity prescription especially when using fixed percentages of HRmax. Changes in HRPC´s were affected by sex and performance, where women generally and subjects with higher performance presented less atypical HRPC´s even at older age.