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Building a prediction model for iron deficiency anemia among infants in Shanghai, China

机译:建设中国上海婴幼儿缺铁性贫血预测模型

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Iron deficiency anemia (IDA) is a common micronutrient deficiency worldwide in infants. Iron deficiency anemia, during infancy, can have long‐lasting detrimental effects on the immune and neural systems; the damage is irreversible. This study aimed to build a prediction model to predict the potential risk of IDA among infants. To collect relevant information for model building, we recruited 528 infants from Fenglin Community Health Service Center in Shanghai, China, and collected the information of infants and their parents by using a structured questionnaire. We also got the blood routine examination results of the infants. Then, we used a multilayer perceptron model (MLP) of the neural network model in IBM SPSS Modeler 18.0 to construct the prediction model. Of the 528 included infants, 80 (15.2%) of them had lower hemoglobin values (110?g/L) and were finally diagnosed with IDA. Based on the accuracy of different models, the model with the highest accuracy rate (97.3%) was chosen, and all the preselected 26 variables were included in the model. After the modeling, the results indicated that the number of months of exclusive breastfeeding was the most important predictive variable, followed by the mother having anemia during pregnancy, and then the number of months of feeding the infant with iron‐fortified rice flour. The model has good sensitivity (100%) and specificity (100%). By using this model, we can predict the potential risk of an infant having IDA and can take the initiative to prevent iron deficiency through the improvement of feeding methods.
机译:缺铁性贫血(IDA)是婴儿全世界常见的微量营养素缺陷。缺铁性贫血,在婴儿期间,对免疫和神经系统产生持久的不利影响;损坏是不可逆转的。本研究旨在建立一种预测模型,以预测婴儿IDA的潜在风险。要收集模型建筑的相关信息,我们招募了来自中国上海的冯林社区卫生服务中心的528名婴儿,并通过使用结构化问卷收集婴儿及其父母的信息。我们还有婴儿的血液常规检查结果。然后,我们在IBM SPSS Modeler 18.0中使用了神经网络模型的多层Perceptron模型(MLP)来构建预测模型。在528个包括婴儿中,其中80(15.2%)血红蛋白值下降(<110〜g / L),最终诊断为IDA。基于不同型号的准确性,选择具有最高精度率(97.3%)的模型,并且模型中包含所有预选的26个变量。在建模后,结果表明,独家母乳喂养的月数是最重要的预测变量,其次是怀孕期间患有贫血的母亲,然后喂养婴儿用铁加固米粉。该模型具有良好的敏感性(100%)和特异性(100%)。通过使用此模型,我们可以预测具有IDA的婴儿的潜在风险,并且可以通过改善饲养方法来预防缺铁的潜力。

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