Dietary Magnesium, Vitamin D, and Animal Protein Intake and Their Association to the Linear Growth Trajectory of Children from Birth to 24 Months of Age: Results From MAL-ED Birth Cohort Study Conducted in Dhaka, Bangladesh

摘要

Background: Evidence suggests lack of understanding of the association of specific nutrients withdifferent time points of linear growth trajectory.Objective: We investigated the role of dietary macro- and micronutrients on length-for-age z (LAZ)score trajectory of children across first 24 months of their life.Methods: The MAL-ED Bangladesh birth cohort study recruited 265 healthy newborn children afterbirth. The linear growth trajectory of those children was modeled using latent growth curve modeling(LGCM) technique.Results: Dietary magnesium intake at 9 to 11 months was positively associated (coefficient b ? 0.006,P .02) with LAZ at 12 months. Animal protein intake at 15 to 17 months, in turn, was positively associated(b ? 0.03, P .03) with LAZ at 18 months. However, vitamin D intake at 15 to 17 months was negativelyassociated (b? 0.06, P .02) with LAZ at 18 months. Other micro- and macronutrients did not show any statistically significant association with the linear growth trajectory. We also found that birth weight(b ? 0.91, P .01), treating water (b ? 0.35, P 0.00), and maternal height (b ? 3.4, P .00) were positivelyassociated with intercept. Gender had a significant negative association with the intercept, but a positiveassociation with the slope (b ? 0.39, P .01; b ? 0.08, P .04), respectively. Conversely, birth weight hadnegative association with the slope (b ? 0.12, P .01).Conclusions: Dietary magnesium and animal protein were positively and vitamin D was negativelyassociated with the linear growth trajectory. Maternal height, birth weight, gender, and treatment ofdrinking water also played significant roles in directing the trajectory