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Liver and Kidney Transplant During a 6-Month Period in the COVID-19 Pandemic: A Single-Center Experience

机译:肝肾移植在Covid-19流行病的6个月内:单中心经验

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Objectives: With the declaration of COVID-19 as a pandemic, many studies have indicated that elective surgeries should be postponed. However, postponement of transplants may cause diseases to get worse and increase the number in wait lists. We believe that, with precautions, transplant does not pose a risk during pandemic. Here, we aimed to evaluate our transplant results, which we safely performed during a 6-month pandemic period. Materials and Methods: Until September 2020, 3140 kidney and 667 liver transplants have been performed in our centers. We evaluated 38 kidney transplants and 9 liver transplants procedures performed during the pandemic (March1 toSeptember 2, 2020).Recipient and donor candidates were screened for COVID-19 with polymerase chain reaction and thoracic computed tomography. All recipients had routine immunosuppressive protocol. During hospitalization at our COVID-19-free transplant facility, we restricted the interactions during multidisciplinary rounds. Results:Duringthepandemic, 38 kidney transplantswith an average length of hospital stay of 8.1 days were performed. Mean serum creatinine values of recipients were 0.91, 0.86, and 0.74 mg/dL on postoperative days 7, 30, and90,respectively.Duringthepandemic, 9 living donor liver transplants (1 adult, 8 pediatric) were performed with an average length of hospital stay of 17.1days. Meanserumtotalbilirubinlevelswere 0.9, 0.5, and 0.4 mg/dL on postoperative days 7, 30, and 90, respectively. Mean serum aspartate aminotransferase levels were 38.1, 28.3, and 22.3 U/L on postoperative days 7, 30, and90,respectively.Allrecipients anddonors were successfully discharged. Only 1 liverrecipient died (onday 55 afterdischarge as a result of oxalosis-induced heart failure). Conclusions:According to ourresults, when precautions are taken, transplant does not pose a risk to patients duringthepandemicperiod.We attribute the safety and success shown to our newly developed protocol in response to the COVID-19 pandemic.
机译:目标:与COVID-19大流行的声明,许多研究表明,急需手术应推迟。然而,移植的推迟可能会导致疾病恶化,并增加在等待列表的数量。我们认为,随着防范措施,移植不会引起大流行期间的危险。在这里,我们的目的是评估我们的移植效果,这是我们在6个月大流行期间安全地执行。材料和方法:直到2020年9月,3140肾和667个例肝移植已经在我们中心进行。我们评估了38个肾移植,并在大流行(March1 toSeptember 2,2020年)和.Recipient施主候选人进行9个肝脏移植程序筛选COVID-19聚合酶链反应和胸部计算机断层摄影。所有受者的免疫程序协议。在我们的COVID-19-免费移植设施住院,我们限制在多学科轮的相互作用。结果:Duringthepandemic,进行了3​​8肾脏transplantswith住院8.1天的平均长度。收件人的平均血清肌酐值分别为0.91,0.86,和0.74 mg / dL的术后天7天,30 and90,respectively.Duringthepandemic,9活体肝移植(1名成人,儿童8)与住院的平均长度进行的17.1天。 Meanserumtotalbilirubinlevelswere 0.9,0.5和0.4毫克/分升术后天7天,30和90,分别。平均血清谷草转氨酶水平38.1,28.3,和22.3 U / L术后天7天,30 and90,respectively.Allrecipients anddonors成功排出。只有1 liverrecipient死亡(onday 55后放电作为oxalosis诱发心脏衰竭的结果)。结论:根据ourresults,采取预防措施时,移植不会对患者duringthepandemicperiod.We属性的风险响应COVID-19大流行表明,我们新开发的协议的安全性和成功。

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