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Adult spinal deformity surgical decision-making score. Part 2: development and validation of a scoring system to guide the selection of treatment modalities for patients above 40years with adult spinal deformity

机译:成人脊柱畸形外科决策得分。第2部分:进展和验证评分系统,以指导成年脊柱畸形40岁以上40岁的患者选择治疗方式

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We aimed to develop and internally validate a scoring system, the adult spinal deformity surgical decision-making (ASD-SDM) score, to guide the decision-making process for ASD patients aged above 40years. A multicentre prospective ASD database was retrospectively reviewed. The scoring system was developed using data from a derivation set and was internally validated in a validation set. The performance of the ASD-SDM score for predicting surgical management was assessed using the area under the receiver operating characteristic curve (AUC). A total of 702 patients were included for analysis in the present study. The scoring system developed based on 562 patients, ranging from 0 to 12 points, included five parameters: leg pain scored by the numerical rating scale; pain and self-image domains in the Scoliosis Research Society-22 score; coronal Cobb angle; and relative spinopelvic alignment. Surgical indication was graded as low (score 0 to 4), moderate (score 5 to 7), and high (score 8 to 12) groups. In the validation set of 140 patients, the AUC for predicting surgical management according to the ASD-SDM score was 0.797 (standard error = 0.037, P 0.001, 95% confidence interval = 0.714 to 0.861), and in the low, moderate, and high surgical indication groups, 23.7%, 43.5%, and 80.4% of the patients, respectively, were treated surgically. The ASD-SDM score demonstrated reliability, with higher scores indicating a higher probability of surgery. This index could aid in the selection of surgery for ASD patients in clinical settings. These slides can be retrieved under Electronic Supplementary Material.
机译:我们旨在发展和内部验证得分系统,成年脊柱畸形外科决策(ASD-SDM)得分,指导40年以上的ASD患者的决策过程。回顾性地审查了多中心潜在ASD数据库。评分系统是使用来自派生集的数据开发的,并在验证集中内部验证。使用接收器操作特性曲线(AUC)下的区域评估了用于预测手术管理的ASD-SDM评分的性能。在本研究中共有702名患者进行分析。评分系统根据562名患者开发,范围从0到12分,包括五个参数:由数值评定量表评分的腿部疼痛;脊柱侧凸研究室的痛苦和自我形象域 - 22分数;冠状角角;和相对旋尖髓相对。手术指示较低(得分0至4),中等(得分5至7),高(得分8至12)组。在验证组140名患者中,根据ASD-SDM评分预测手术管理的AUC为0.797(标准误差= 0.037,P <0.001,95%置信区间= 0.714至0.861),低,中等,和高手术指示群,分别进行23.7%,43.5%和80.4%的患者进行手术治疗。 ASD-SDM评分证明了可靠性,得分更高,表明手术较高概率。该指数可以帮助选择临床环境中ASD患者的手术。这些幻灯片可以在电子补充材料下检索。

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