Phylosymbiosis, diet and gut microbiome-associated metabolic disease

摘要

Microbiomes are influenced both by hostevolutionary history and ecological context.Phylosymbiosis has been proposedas a framework to understand how evolutionaryrelationships among hosts predictthe structure of the gut microbiome [1]. Inthis scenario, a hierarchical tree of similaritiesamong host-associated microbiomeswould mirror a phylogenetic tree of evolutionaryrelationships among hosts(Fig. 1). Phylosymbiosis can arise throughcoevolution and also through environmental,dietary or physiological similaritiesthat correspond with sharedevolutionary history.