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Predictors of high school dropout, anxiety, and depression in genetic generalized epilepsy

机译:高中辍学,焦虑和抑郁症的预测因素在遗传广义癫痫中的抑制作用

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Affective disorders are overrepresented in epilepsy, and people with epilepsy may be at risk of dropping out from school. The aim of the present study was to assess factors influencing high school dropout, anxiety, and depression in genetic generalized epilepsy (GGE). One hundred and ten people with GGE aged 19‐40?years underwent a clinical interview, including the Hospital Anxiety and Depression Scale (HADS) questionnaire. Potential predictors of high school dropout were analyzed with logistic regression, and factors influencing total HADS score were analyzed with linear regression. Having felt excluded because of epilepsy was significantly associated with high school dropout (odds ratio 7.80, P =?.009), as was total HADS score (odds ratio 1.22, P =?.005). If a participant was currently employed or undergoing education, previous high school dropout was less likely (odds ratio 0.07, P =?.005). High school dropout was associated with increased current anxiety and depression ( β =?0.32, P =?.005). Epilepsy severity (current drug resistance, current polytherapy, and active generalized tonic‐clonic seizures) was not associated with high school dropout, nor with total HADS score. The issue of stigma in epilepsy must be thoroughly addressed in comprehensive care and may be as important as seizure control when it comes to education and quality of life.
机译:情感障碍在癫痫中持久化,癫痫的人们可能面临从学校辍学的风险。本研究的目的是评估影响高中辍学,焦虑和抑郁症遗传广泛性癫痫(GGE)的因素。 19-40岁的GGE一百十万人?多年的临床采访,包括医院焦虑和抑郁症(曾)问卷。利用Logistic回归分析了高中辍学的潜在预测因子,并用线性回归分析了影响总量的因素。由于癫痫患者与高中辍学有显着相关的感觉被排除(赔率比7.80,p =Δ.009),因此总有得分(差距1.22,P = 005)。如果参与者目前就业或接受教育,之前的高中辍学可能不太可能(赔率比0.07,P = 005)。高中辍学与目前的焦虑和抑郁症增加有关(β= 0.32,P =Δ.005)。癫痫严重程度(目前的耐药性,目前的抗药性和有效的广义滋补克隆癫痫发作与高中辍学没有相关,也没有总数得分。癫痫中的耻辱问题必须在综合性护理中彻底解决,并且在涉及教育和生活质量时,可能会像癫痫发作一样重要。

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