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Simultenous Voltammetric Detection of Acetaminophen and Tramadol using Molybdenum Tungsten Disulfide-Modified Graphite Screen-Printed Electrode

机译:使用钼钨二硫化石墨丝网印刷电极同时伏安检测对乙酰氨基酚和曲马多的检测

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摘要

Nanopetal-structured molybdenum tungsten disulfide (MTD) have been successfully synthesized and applied as a very good modifier for constructing a new and strongly sensitive electro-chemical sensing ground for concurrent detection of two crucial pain reliever medicines, acetaminophen and tramadol. XRD, EDX and SEM have been employed for characterizing synthesized nanoparticles. A comprehensive examination by electro-chemical techniques, including differential pulse voltammetry (DPV) and cyclic voltammetry (CV) has been conducted for clarifying electro-catalytic features of nanopetals by modify graphite screen printed electrode (SPE). Under the optimal condition, the MTD/SPE provided linearly responses in range between 0.04-600.0 and little determination limit of 12.0 nM for acetaminophen. Accurate and sensitive concurrent detection of acetaminophen and tramadol in biological samples and medicine formulations validated the suggested sensor reliability.
机译:纳米甲醛结构钼钨(MTD)已成功合成并应用为非常好的改进剂,用于构建新的和强烈敏感的电化学传感接地,用于两种关键止痛药,对乙酰氨基酚和曲马多的同时检测。 XRD,EDX和SEM已用于表征合成的纳米颗粒。已经通过改变石墨丝网印刷电极(SPE)来进行通过电化学技术,包括差分脉冲伏安法(DPV)和循环伏安法(CV)的综合检查,包括通过改变石墨丝网印刷电极(SPE)来澄清纳米络的电催化特征。在最佳条件下,MTD / SPE在0.04-600.0的范围内提供线性响应,乙酰乙酰氨基酚的4.0nm的测定极限很小。在生物样品和药物配方中的乙酰氨基酚和曲马多的乙酰氨基酚和曲马多的准确和敏感的并发检测验证了建议的传感器可靠性。

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