Gout is condition in which person become immobile and inactive due to joint pains and swelling. Gout occurs, when urate crystal deposition of in the joints. Vatarakta is considered as a vata pradhana vyadhi and rakta dushti. Gokshuradi Guggulu is having vatahara and raktashodhak properties. Guduchi kwatha selected as anupana because of its Rasayana, Vatashamaka, Balya, vedana sthapana and Ama pachana properties will help to disrupt the Samprapti vighatana of vatarakta. The objectives of the study were to evaluate the effect of Gokshuradi Guggulu with Anupanabheda in the management of Vatarakta and to compare the result of both groups. This study was randomized, parallel comparative clinical trial of two groups each of 20 patients. From OPD of DBACH Mandigobindgarh; 40 patients of vatarakta taken which were randomly divided into two groups. Group A, 20 patients for 60 days received Gokshuradi Guggulu 1 gm. BD with lukewarm water and Group B,20 patients received Gokshuradi Guggulu 1gm BD with Guduchi Kwatha for 60 days. In Group A, among 20 patient’s 55% patients showed moderate response and 45% patients showed mild response. In Group B among 20 patients, 95 % patients showed moderate response and 5 % patients showed mild response. Both shows statistically highly significant results in both subjective and objective except erythema & discoloration. Treatment modality in Group B (i.e. Gokshuradi Guggulu with Guduchi Kwatha) is effective in comparison of treatment modality in Group A (i.e. Gokshuradi Guggulu with lukewarm water).
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