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Pharmaceutical Modification of Kasisadi Churna to Varti and its Physicochemical Analysis

机译:Cassiyudi通过Threcina和其他Fasis化学分析的药物改性

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Background: Kasisadi churna is a yoga (formulation) mentioned for treatment of kaphaja yoni vyapath (vulvo vaginal candidiasis) which is applied as lepa along with honey. But the administration of the drug through vaginal route in this form is highly discomforting. Modification of a dosage form is essential for the enhancement of efficacy, acceptability of the product and shelf life. Materials and Methods: Varti is prepared from the drugs of kasisadi churna in three methods, bhavana method (KV1), gudapaka method (KV2) and modified method (KV3) with the addition of cocoa butter as base. The prepared samples were tested for analytical parameters. Result and Discussion: Kasisadi churna can be easily modified into varti form. Preparation of KV2 was easy, gives more yield in less time and better in organoleptic features and disintegration time compared to KV1 and KV3. Conclusion: The results of the pharmaceutical and analytical study can be considered as the preliminary standards for the preparation of Kasisadi Varti.
机译:背景:Kasisadi Churna是用于治疗Kaphaja Yoni Vyapath(外阴阴道念珠菌病)的瑜伽(配方),其与蜂蜜一起施用作为LEPA。但通过这种形式的阴道途径给药给药是非常不舒服的。剂型的改性对于提高功效,产品和保质期的可接受性是必不可少的。材料和方法:Varti以三种方法,Bhavana方法(KV1),GudaPaka方法(KV2)和改性方法(KV3)制备,加入可可脂作为碱。测试制备的样品进行分析参数。结果和讨论:Kasisadi Churna可以很容易地修改到Varti形式中。与KV1和KV3相比,KV2的制备容易易于在更少的时间内递增,并且在较短的时间内较少,并且崩解时间更好。结论:药物和分析研究的结果可被视为制备Kasisadi Varti的初步标准。

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