Feasibility of Beans/Bran Enriching Nutritional Eating For Intestinal Health & Cancer Including Activity for Longevity: A Pilot Trial to Improve Healthy Lifestyles among Individuals at High Risk for Colorectal Cancer

摘要

Purpose: Examine the feasibility and preliminary effects of a lifestyle intervention of rice bran plus navy bean supplementation, and physical activity (PA) education on intake of fiber and whole grains, and PA levels. Design: Randomized-controlled, single-blinded. Setting: Academic institution and free-living. Subjects: Adults 18?years, with ≥1 adenomatous polyp removed within 3?years. Intervention: Participants received powder and pre-prepared meals and snacks that contained either rice bran (30?g/day) plus navy bean (30?g/day), or Fibersol-2 ? (10?g/day), for 12-weeks. All participants received a 1-hour (PA) education session. Measures: Feasibility was assessed by recruitment and retention rates, and compliance to the study foods and procedures. Three-day food logs were analyzed using Nutritionist Pro? to estimate fiber intake, and the Automated Self-Administered 24-hour (ASA24 ? ) Dietary Assessment Tool calculated Healthy Eating Index (HEI) whole grain and total scores. PA was measured using an ActivPAL? accelerometer. Analysis: Continuous data were summarized as median, range, and percent change from baseline to post-intervention. Results: N?=?20 (86.9%) completed the intervention. Compliance was 92% in the rice bran plus navy bean versus 89% in Fibersol-2 ? . Navy bean consumption increased from 2?g/day to 30?g/day, and rice bran from 0?g/day to 30?g/day. Fiber intake (g/day) increased by 73% versus 82%, HEI whole grain improved by 270% versus 37%, and HEI total improved by 10% versus 9.1% in rice bran plus navy bean and Fibersol-2 ? , respectively. Total PA (MET-hours/day) showed minimal change for intervention ( 0.04%) and control ( 4%). Conclusion: Findings merit a larger trial of rice bran plus navy bean and PA to evaluate efficacy for dietary and cancer prevention-related outcomes.