Purpose: This study was launched to assess COVID-19-related knowledge, attitude and practice among hospital and community pharmacists in Addis Ababa, Ethiopia. Methods: Self-administered questionnaire was distributed to pharmacists working in hospitals and community pharmacies by physically delivering the questionnaire to study subjects. Data collected were entered into and analyzed by IBM SPSS Statistics ? Version 25. Binary logistic analysis was used to determine the association between independent and outcome variables. Results: All 295 participants who completed the survey stated that they had heard about COVID-19. Almost all of the participants were aware of the causative agent, the clinical manifestations and the ways of transmission of COVID-19. Most participants (92.2%) identified elderly individuals as one of the high-risk groups for severe complications and death while 89.5% identified supportive therapy and life support as recommended management options to date. More than half (53.2%) of the respondents were found to have adequate knowledge about COVID-19. Among respondents, 89.8% had a positive attitude on the importance of following WHO recommendations in reducing the transmission of COVID-19. Only 9.8% had confidence in the capacity of healthcare facilities in the country to properly handle potential COVID-19 pandemic. Inadequate protective measures were taken to protect the staff from COVID-19 in the institutions of 70.2% of the participants. Among the WHO recommended prevention measures, hand washing was exercised by 97.3% of the study participants. Conclusion: The study findings confirmed that there is a high level of knowledge on each specific aspect of COVID-19 among the study participants. However, only about half of the participants had adequate knowledge about the disease. The pharmacists showed a predominantly positive attitude towards the importance of WHO recommendations and predominantly negative attitude towards the country’s capacity to deal with the pandemic. The practice related to COVID-19 was inadequate at institutional level. Nevertheless, most of the pharmacists individually exercised self-protective measures against COVID-19. All stakeholders should work on ensuring the adequate supply of materials and services that aid in controlling the pandemic.
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