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Randomized Controlled Trial of Tailored Music Listening Intervention for Sleep in Dementia

机译:痴呆睡眠睡眠量身定制的音乐听力干预的随机对照试验

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Abstract Sleep disruption in older adults living with Alzheimer’s disease and related dementias (ADRD) is debilitating and contributes to increased institutionalization, reduced cognitive function, and accelerated disease progression. Given the potential harmful effects of pharmacologic treatment, non-pharmacologic approaches, such as music, may provide a safer alternative to improve sleep quality in this vulnerable population. No empirically validated music protocol exists to address sleep disruption in older adults with ADRD living at home. Therefore, the specific aims of this wait-list randomized controlled trial were to examine the 1) feasibility; 2) acceptability; and 3) preliminary efficacy of a tailored music intervention in home-dwelling older adults with ADRD with sleep disruption and their caregivers. This presentation focuses on baseline characteristics of dyads, which included persons with ADRD and their caregivers who have completed the clinical trial so far (N=28). The mean age of persons with ADRD was 71.6 (SD: 7.6). The mean age of caregivers was 58.7 (SD: 16.7). Sixty-eight percent (n=19) of persons with ADRD were female. Similarly, the majority of caregivers were female (n=20, 71.4%). Seventy-four percent of persons with ADRD scored 0.5 on the Clinical Dementia Rating instrument, indicative of very mild dementia. The majority of dyads identified themselves as non-Hispanic (92%). Seventy-nine percent of persons with ADRD identified themselves as Black or African-American (n=22, 79%), while 82.1% of caregivers identified themselves as Black or African American. Preliminary analysis of qualitative data indicates high acceptability of the intervention. Results from this research study will inform a future efficacy trial.
机译:摘要患有阿尔茨海默病和相关痴呆症(ADRD)的老年人的睡眠中断正在衰弱,并有助于增加制度化,减少认知功能和加速疾病进展。鉴于药理学治疗的潜在有害影响,诸如音乐等非药理学方法,可以提供更安全的替代方案,以改善这种脆弱的人群中的睡眠质量。没有经验验证的音乐协议存在,以解决在家里的Adrd的老年人中睡眠中断。因此,这种等待列表随机对照试验的具体目标是检查1)可行性; 2)可接受性; 3)定制音乐干预在家庭住宅的老年人与ADRD的初步疗效,睡眠中断和护理人员。本演示文稿侧重于二元的基线特征,其中包括迄今为止已完成临床试验的ADRD及其护理人员(n = 28)。 ADRD人的平均年龄为71.6(SD:7.6)。护理人员的平均年龄是58.7(SD:16.7)。六十八分(n = 19)的adrd人员是女性。同样,大多数护理人员是女性(n = 20,71.4%)。患有ADRD的百分之七十四名人员在临床痴呆评级仪器上得分为0.5,指示非常轻微的痴呆症。大多数二元证实自己是非西班牙裔(> 92%)。 Adrd的百分之九九百分之一人认为自己是黑人或非裔美国人(n = 22,79%​​),而82.1%的护理人员认为自己是黑人或非洲裔美国人。定性数据的初步分析表明干预的高可接受性。这项研究的结果将向未来的疗效试验提供信息。

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