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High-Risk Medication Use and Polypharmacy in Older Veterans Who Attempt Suicide

机译:在老退伍军人试图自杀的高风险药物用途和多药地

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Abstract Late-life veteran suicide is a public health concern, and may overlap with recent high-risk medication use. We identified use in the 6 months prior to attempt and assessed salient risk factors. 13,872 veterans aged 50 years and older that attempted suicide were compared with demographically-matched controls utilizing VHA healthcare in a similar time period. Medications potentially related to suicide risk were included. Other variables were psychiatric and medical diagnoses, fatality of attempt and means. Compared with controls, veterans who attempted were nearly 3 times more likely to have been prescribed benzodiazepines and opioids, even when controlling for other diagnoses. Those taking 3 or more high-risk medications were between 7 and 11 times more likely to attempt than controls, with a higher risk of death particularly by drug overdose. These findings begin to uncover the complex contribution of prescription medications and polypharmacy to late-life veteran suicide, with implications for prevention. Part of a symposium sponsored by the Aging, Alcohol and Addictions Interest Group.
机译:摘要寿命退伍军人自杀是公共卫生的关注,并且可能与最近的高风险药物用途重叠。我们在尝试前6个月内识别使用并评估突出危险因素。在类似时间段内使用VHA医疗保健的人群匹配的对照,将自杀的13,872岁及以上试用的退伍军人。包括与自杀风险有关的药物。其他变量是精神病和医学诊断,尝试的致命和手段。与对照相比,即使在控制其他诊断时,尝试的退伍军人均近3倍可能被规定的苯并二氮杂卓和阿片类药物。服用3种或更多的高风险药物的人比对照组的可能性比对照更少7至11倍,尤其是药物过量的死亡风险较高。这些调查结果开始揭示处方药物和多酚武术对后期退伍军人自杀的复杂贡献,具有预防的影响。由衰老,酒精和成瘾兴趣组赞助的研讨会的一部分。

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