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Relation of Clinical Features with Microbiological Findings in Children of Suspected Pulmonary Tuberculosis

机译:临床特征与涉嫌肺结核儿童微生物发现的关系

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Introduction: Tuberculosis (TB) is an important cause ofmorbidity and mortality in children especially in TB endemicsettings. In endemic regions of TB, it is a major yet anunrecognised factor for death among children. Childrenare usually assessed when they present with symptoms orsigns associated with TB. The standard tuberculin test canbe used as an adjunct in diagnosing TB in children, howeverdefinitive proof for lesion being of tuberculous origin is findingof tubercle bacilli.Aim: To determine the association between the clinicalfeatures in suspected pulmonary TB with sputum positivity.Materials and Methods: Mantoux test for every childsuspected to be suffering from TB was done. X-ray radiographywas done and findings were recorded from December 2017to June 2019. Two sputum samples were collected fromevery suspected case. One in a sterile specimen cup with atight-fitting cap was sent for Ziehl-Neelsen staining and theother in a falcon tube was sent for Cartridge Based NucleicAcid Amplification Test (CBNAAT). The data was analysedusing Microsoft SPSS version 26.0 and along with graph padprism software.Results: Out of 53 subjects, 10 patients (19%) tested positivefor acid fast bacilli via Ziehl-Neelsen staining as well asCBNAAT and remaining 43 patients (81%) tested negative.Mantoux test results were not significantly different from thepercentage of patients with sputum negativity (93.02%). Thepercentage of sputum positive patients with cavitations onchest X-ray was 70% which was significantly higher.Conclusion: Females were more likely to suffer from TBdisease as compared to the males. Sputum positivity wassignificantly associated with cavitatory lesion on chest X-ray.
机译:介绍:结核病(TB)是儿童中的一种重要原因,特别是在TB Nexemicsettings中。在结核病的地方性地区,它是儿童死亡的一个主要又一个严重的因素。儿童常常在患有与结核病相关的症状时评估。标准结核蛋白检验可以用作诊断儿童结核病的辅助,但是损伤是结核病的损伤的证据是聚结节杆菌的疾病:确定患有痰阳性的疑似肺结核的临床治疗之间的关联。材料和方法:Mantoux完成了每童水的测试完成了。完成了X射线放射线造影和调查结果从2017年12月开始记录。从疑似案件中收集了两种痰样品。在具有可明确配合盖的无菌标本杯中被送入Ziehl-Neelsen染色,并且捕获基于盒的核酸核酸扩增试验(CBNAAT)中的猎鹰管中的其他。该数据进行了分析了Microsoft SPSS版本26.0,以及图形Padprism软件。结果:53名受试者,10名患者(19%)通过Ziehl-Neelsen染色测试阳性酸氨酸,并剩下43名患者(81%)测试负数与痰消极患者的表达(93.02%)没有显着差异。痰阳性阳性患者的阳性阳性X射线是70%显着提高。结论:与雄性相比,女性更容易患有TBDisease。痰阳性与胸部X射线上的空腔病变相关。

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