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A simple method for inducing nonalcoholic steatohepatitis with fibrosis

机译:一种用纤维化诱导非酒精性脂肪性肝炎的简单方法

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Background Nonalcoholic fatty liver disease (NAFLD) is increasingly occurring in sedentary people, and may progress to NASH and hepatocellular carcinoma. It is essential to design affordable animal models for the study of various diseases, including fatty liver, which was the aim of the study. In this study, a high‐fat diet was devised that triggers NASH's animal model quickly and easily. High‐fat diet (HFD) was used both with intra‐mouth oral gavage and in combination with animal pellets.
机译:背景技术非酒精性脂肪肝疾病(NAFLD)越来越多地发生在久坐不动的人中,并且可能进化到肿瘤和肝细胞癌。对于研究各种疾病,包括脂肪肝的研究是必要的,这是该研究的目的。在这项研究中,设计了高脂肪的饮食,迅速轻松地触发了纳什动物模型。高脂饮食(HFD)用口腔口腔饲料和动物颗粒组合使用。

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