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Ischemic colitis in a patient with chronic kidney failure: case report

机译:患有慢性肾功能衰竭的患者的缺血性结肠炎:案例报告

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Introduction. Ischemic colitis develops due to acute reduced blood flow through the colon and appearance of secondary reperfusion injuries. Patients dependent on renal replacement therapies are at highest risk because of frequent periods of hypotension and hypoperfusion, related to haemodialysis. Case presentation. A 66-year-old female patient, with history of stage 4 chronic kidney disease (CKD), presented for haemorrhagic shock following occult gastrointestinal bleeding and secondary acute posthaemorrhagic anaemia. Because of multiple systemic dysfunctions, she was admitted into the intensive care unit (ICU). Continuous renal replacement therapy with cytokine filter was performed, to reduce the level of circulating inflammatory markers. A computed tomography examination was performed, that established the diagnosis of ischemic colitis and she underwent subtotal colectomy with terminal ileostomy. The evolution was favourable, and after 10 days she was transferred from the ICU to the surgical ward. After another 5 days, she returned to the previous functional status and was discharged. Conclusions. Ischemic colitis can lead to lower gastrointestinal bleeding and even to haemorrhagic shock, especially in patients with chronic kidney disease, intermittent hemodialysis, atherosclerotic diseases, heart failure and diabetes mellitus.
机译:介绍。缺血性结肠炎由于急性降低的血液流过结肠癌和二次再灌注损伤而出现而发展。由于血液透析有关的频繁的低血压和低血量,依赖于肾置换疗法的患者处于最高风险。案例演示。一名66岁的女性患者,患有第4阶段慢性肾病(CKD)的历史,患有血液胃肠出血和继发性急性假血症贫血后的出血性休克。由于多种全身性交功能,她被录取到重症监护室(ICU)中。进行连续肾置换疗法,进行细胞因子过滤器,以减少循环炎症标志物的水平。进行了计算的断层扫描检查,确定了缺血性结肠炎的诊断,她接受了末端对末端术语的脑膜切除术。进化是有利的,在10天后,她从ICU转移到外科病房。另外5天,她返回以前的功能状态并被解雇。结论。缺血性结肠炎可导致胃肠道出血,甚至血液抑制,特别是在慢性肾病,间歇性血液透析,动脉粥样硬化,心力衰竭和糖尿病患者中。

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