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Diagnostic approach using the original Geneva score of pulmonary thromboembolism in pregnancy

机译:诊断方法使用妊娠期肺血栓栓塞的原始日内瓦评分

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Introduction. Pulmonary embolism is an important public health problem in both developing and industrially developed countries. Diagnosis and management of pulmonary embolism remain a challenge for the current obstetrics practice, due to pregnancy-associated symptoms, which are sometimes similar to those of venous thromboembolism. The gold standard for diagnosis is computed tomography (CT) pulmonary angiography/ ventilation perfusion scanning, which imply radiation exposure for mother and fetus. Administration of “blind” anticoagulant therapy in pregnant women may increase the risk of hemorrhagic complications. The major challenge in these cases is to decide when angiography is really needed. Several algorithms and scores are proposed to avoid imaging techniques in these patients. The objective of the study was to evaluate local practices regarding the diagnosis of venous thromboembolism in the department of Obstetrics and gynecology of Louis Dommergues Hospital, Trinity, Martinique, and to compare them with the existing international guidelines. Material and methods. Presentation of series of cases with suspicion of venous thromboembolism investigated in the Department of Obstetrics and Gynecology of “Louis Dommergues” Hospital, Trinity, Martinique. Results . Initial diagnostic testing (electrocardiogram, blood gases, D-dimers, troponine, NT-proBNP) was performed for all pregnant patients presenting clinical suspicion of PE. According to the original Geneva score, the majority of patients had a high risk of PE ( 8 points) – 4 (44.44%) and 3 (33.33%) – intermediate (5 – 8 points) and 2 (22.22%) – low-risk of PE (0 – 5 points). PE was confirmed by angio-TC in 2 patients (22.22%). Conclusions . Clinical suspicion of pulmonary thromboembolism should lead to imaging techniques as CT angiography or ventilation/perfusion scanning. Abnormal blood gases, D-dimers, NT-pro BNP or electrocardiogram are not sufficient to confirm nor to invalidate the diagnosis.
机译:介绍。肺栓塞是发展中国家和工业发达国家的重要公共卫生问题。由于妊娠相关症状,肺栓塞的诊断和管理仍然是目前妇产实践的挑战,这有时与静脉血栓栓塞的栓塞有时类似。诊断的金标准是计算机断层扫描(CT)肺血管造影/通风灌注扫描,这意味着母亲和胎儿的辐射暴露。孕妇中“盲人”抗凝血治疗的施用可能会增加出血性并发症的风险。这些案例中的主要挑战是决定何时需要血管造影。提出了几种算法和分数以避免这些患者的成像技术。该研究的目的是评估关于Louis Dommergue医院,三一,马提尼克州路易斯多尔尼医院妇产科静脉血栓栓塞栓塞的局部做法,并将其与现有的国际指南进行比较。材料与方法。介绍伴随着静脉血栓栓塞的系列案件,在“路易斯多闻”医院,三位一体,马提尼克州妇产科。结果 。对呈现PE临床怀疑的所有妊娠患者进行初始诊断测试(心电图,血液,D二聚体,肌钙蛋白,NT-PROPNP)。根据原来的日内瓦评分,大多数患者的患者风险高(> 8分) - 4(44.44%)和3(33.33%) - 中间体(5-8分)和2(22.22%) - 低 - PE(0 - 5分)。在2名患者中,通过血管Tc确认PE(22.22%)。结论。肺血栓栓塞的临床疑似应导致成像技术作为CT血管造影或通风/灌注扫描。异常血液,D-二聚体,NT-Pro BNP或心电图不足以确认,也不足以使诊断无效。

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