Comparative economic efficiency of using pharmacological agents for the stress prevention in the course of immunization of birds against reovirus tenosynovitis

摘要

This article describes the results of studies on the definition and comparative evaluation of the effectiveness of using SPAO-FA (stress protector antioxidant – feed additive) and SPAO-complex pharmacological preparation (stress protector antioxidant – complex preparation for birds) for the prevention of vaccine stress during immunization of birds against reovirus tenosynovitis. These preparations were used during 5 days (3 days before vaccination, on the day of vaccination and one day after vaccination) at the dose of 185 mg kg-1 body weight: SPAO-FA was given as a part of compound feed, SPAO-complex – with water. Stress prevention in chickens of the parent flock provides equally high level of protection of birds from a field virus, a causative agent of reovirus tenosynovitis: it reduces the development of a protective level of antibodies by 7 days. Using SPAO-complex contributed to the increase in antibody titers by a factor of 2.6, and to the decrease in the coefficient of variation by the term of monitoring immunity stress by 25.7%. Using SPAO-FA increased antibody titers by 1.6 times, but had no significant effect on vaccination homogeneity. Vaccination index that should be high in the case of successful vaccination was 3.5 times higher for SPAO-complex in comparison with the basic diet; this for SPAO-FA was 1.6 times higher. Positive effect of anti-stress therapy influences the livability of chickens which was 3.5% higher with SPAO-complex, 0.79% higher – with SPAO-FA; bird live weight and the yield of day-old chicks were also higher in comparison with the basic diet by 6.44 and 0.88%, and 4.22 and 0.55%, respectively. Cost-effectiveness of using SPAO-FA per RUR of costs amounted to 180.09 RUR, for SPAO-complex, this parameter amounted to 435.86 RUR.