Hypospadias is a very common congenital anomaly in which the urethra opens onto the ventral aspect of the penis rather than at the tip. It has an incidence of less than 1% of live male births. In humans, anogenital distance (AGD) is a sexually dimorphic measure of genital development. In this study, we intended to examine the association between AGD and hypospadias using a homogenous group of patients. The same investigator examined all male newborns in our hospital, and anthropometric measurements of the anogenital distance were recorded. All the measurements were made in millimeters (mm) with a sliding digital caliper (graduated in millimeters) used for measuring the distance between the base of the scrotum to the center of the anus; defined as AGD. During the period Jan 2015 to December 2019 (both inclusive), there were 28,426 (14,615 males and 13,811 females) full-term live births in our hospital. The gestational age of the newborns ranged from 37 to 42 weeks. The mean AGD was 21.065.57 (range 12.11 to 33.14) mm in newborns without hypospadias, 9.921.90 (range 8.0 - 13.9) in newborns with proximal hypospadias and 17.031.95 (range 14.0 to 19.9) mm with distal hypospadias. In humans, hypospadias is associated with reduced anogenital distance. AGD further decreases with the severity of hypospadias.
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机译：Hypospadias是一个非常常见的先天性异常，尿道在阴茎的腹侧方面而不是尖端。它的发生率不到1％的活男性出生。在人类中，胃部距离（AGD）是生殖器发育的性三维措施。在这项研究中，我们旨在使用患者均质组检查AGD和Hypospadias之间的关联。同一调查员在医院检查了所有雄性新生儿，记录了胃部距离的人体测量。所有测量均以毫米（mm）制成，具有滑动数字卡钳（刚刚以毫米），用于测量阴囊底部到肛门中心之间的距离;定义为agd。在2015年1月至2019年12月期间（包括包容性）期间，我们医院的全长活产出28,426名（14,615名男性和13,811名女性）。新生儿的孕龄范围从37到42周。在Newborss的新生儿中，平均agd为21.065.57（范围为12.11至33.14）mm，Newborss，9.921.90（范围8.0-13.9），其中新生儿与近端腹盆多伏裂，17.031.95（范围为14.0至19.9）mm mm mm。在人类中，Hypospadias与源性降低的距离有关。 agd进一步降低了kepospadias的严重程度。
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