Airway clearance ameliorated the control of diffuse panbronchiolitis accompanied by asthma and leukocytoclastic vasculitis

摘要

Asthma is occasionally complicated with bronchiectasis or diffuse panbronchiolitis (DPB), which makes asthma or asthma- like symptoms difficult to control, potentially owing to subclinical infection or bacterial colonization. 1 Here, we present a case of difficult-to-treat asthma comorbid with DPB or protracted bacterial bronchiolitis that was resistant to macrolide therapy and resulted in cutaneous leukocytoclastic vasculitis (CLV). All conditions dramatically improved after the induction of Acapella?, an oscil- lating positive expiratory device, which facilitates airwayclearance.